How to get pregnant with unexplained infertiity

Your goal is to become a parent. Period. Preferably in the fastest, cheapest, and safest way possible. The goal is straight forward, unfortunately the implementation is not. The fastest way to get pregnant with unexplained infertility may surprise you.

We talked about How Long to Try With Fertility Pills and IUI Before Moving to IVF on a Creating a Family Radio Show.


Not “One Size Fits All” for Unexplained Infertility

Of course, the answer to how to get pregnant with fertility treatment depends on your diagnosis and your age. A lot of people continue to think that infertility treatment is like a conveyor belt: enter the door; 3 months of fertility pills (Clomid, Letrozole), 3 months of fertility pills with artificial insemination (IUI), 3 months of IUI with injectable gonadotropins, and then IVF. It’s just not that simple with any diagnosis and it certainly is not that simple with unexplained infertility.

The Fastest Way to Get Pregnant with Unexplained Infertility May Surprise You

The FASTT (Fast-track and Standard Treatment Trail), showed that infertility patients diagnosed with unexplained infertility were able to get pregnant faster and saved an average of $2,600 by bypassing intrauterine insemination (IUI) with injectable ovulatory stimulating drugs (gonadotropins) and going straight to in vitro fertilization (IVF). In theory this approach would also be safer because of fewer multiple births. This study was led by Dr. Richard Reindollar with patients from Boston IVF.  Dr. Alison Zimon, a reproductive endocrinologist at Boston IVF, talked about the findings of this study on the Creating a Family Radio Show.

Who Benefits from Clomid (and other Fertility Pills)

We also talked with Dr. Zimon and Dr. Samantha Pfeifer, Associate Professor of Obstetrics and Gynecology at University of Pennsylvania Medical School, about who should use Clomid, Letrozole, and other infertility pills. When should they be used, by whom, and for how long? This should be must listening for those just beginning on the infertility treatment journey.

How many rounds of Clomid or IUI did you do before moving to IVF?

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First published in 2014. Updated in 2016.