What Are Your Chances of Getting Pregnant With Unexplained Infertility

If you have unexplained infertility, what are your chances of ultimately having a baby — either through infertility treatment or natural conception? We talk with Dr. Denis Vaughan, a board-certified Reproductive Endocrinologist at Boston IVF and a Clinical Instructor at Harvard Medical School. He was the principal investigator on the study “Long-term reproductive outcomes in patients with unexplained infertility”.

In this episode, we cover:

  • What year was the original FASTT trial and what were the findings?
  • What is unexplained infertility and how common is it?
  • Did most of the women try to conceive after the original FASTT trial?
  • How did the women who agree to participate in this follow-up study compare to the original FASTT participants? Was there a difference between those who participated in the follow-up and those who did not?
  • What percentage of the women were successful at conception with IUI? IVF? Natural conception?
  • What percentage tried to conceive with donor egg?
  • What percentage adopted?
  • If the woman had conceived via fertility treatment in the original FASTT trial is she more likely to conceive successfully in the future?
  • Some speculate that a significant proportion of unexplained infertility is due to un-diagnosed endometriosis. Did this follow-up study shed light on that question?
  • Did many of the women after the original FASTT study receive a more definitive diagnosis of why they were not able to conceive?
  • What did the study show about patient satisfaction with their family building process and ultimate family size?
  • What did we learn about conception with unexplained infertility as a result of the follow-up to the FASTT study?

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Music Credit: Michael Ashworth

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