Exciting  research published in The New England Journal of Medicine and Human and Molecular Genetics journals, demonstrates that both Premature Genetic Connection for premature menopause and low sperm countOvarian Failure and azoospermia (very low or absent sperm count) have a genetic connection caused by a mutation of a specific gene. Mutations to the STAG3 gene have been associated with POF and azoospermia in mice, but these studies confirms association in humans.