Epigenetics in Fertility and Infertility Treatment

How can epigenetic changes affect your fertility or the health of your child conceived by fertility treatment? We talk with Dr. Jason Franasiak, a board certified Obstetrician Gynecologist, board certified Reproductive Endocrinology and Infertility specialist, board certified High Complexity Laboratory Director in Embryology and Andrology, and lead physician of RMA’s Marlton Clinic and Lab in South Jersey. He has authored and contributed to over 100 peer reviewed publications, published chapters and abstracts. He serves on the Editorial Board for Fertility and Sterility and the British Journal of Obstetrics and Gynecology.

In this episode, we cover:

What is epigenetics?
What factors can influence or affect the epigenome?
Can we “see” epigenetic changes?
How do epigenetic factors impact our health?
What are the genetic and epigenetic factors associated with female infertility?
What are the genetic and epigenetic factors associated with female PCOS?
What are the genetic and epigenetic factors associated with endometriosis?
What are the genetic and epigenetic factors associated with primary ovarian insufficiency?
What are the genetic and epigenetic factors associated with male infertility?
How could epigenetics affect modifications in invitro fertilization and invitro embryo development?
Imprinting disorders
Do environmental factors affect epigenetics?
What are epigenetic disorders?
Are children conceived by IVF more likely to have epigenetic disorders?
Can epigenetic changes be heritable across generations?